Ovarian Cancer
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Primary ovarian cancer ranks as one of the common causes of cancer deaths in women. Carcinomas are more common in single women and in nulliparous married women. Tumors of germ cell origin are seen in children and teenagers. Women with breast cancer have an increased incidence of ovarian cancer. The symptoms of early cancer are non-specific, hence the majority present with advanced disease. Prognosis varies with the histologic type and staging of the disease, but is generally poor because ovarian tumors tend to progress rapidly. Three main types of ovarian cancer exit primary epithelial tumors (arising in mullerian epithelium), Germ cell tumors (in the ovum itself) and cord (stromal) tumors (ovary’s supporting frame work). Ovarian tumors is noticeably higher in women of upper socioeconomic level between ages 40 and 65, and in single women. A history of endometrial cancer seems to be linked with ovarian cancer. Ovarian cancer can be diagnosis by surgical exploration, clinical evalution, histological studies and patients history. Surgical removal of as much tumor as possible should be attempted. Varying combinations of surgery, chemotherapy, radiotherapy, immunotherapy (BCG vaccination) and endocrine therapy are attempted as per stage of the disease and the patient’s age. Doxorubicin plus Cyclophosphamide with or without cisplatin is good combination chemotherapy. |