Archive for April, 2008

IMMUNITY IN HEALTH AND DISEASE

The prime function of immune system is to protect the host against the invading pathogens. The body tries its best to overcome various strategies of infectious agents (bacteria, viruses), and provides immunity. Some of the important immunological aspects in human health and disease are briefly described.

HPLC Has Permitted Greatly Improved Separations

The separations are greatly improved, however, through the use of high-resolution columns and the column retentions times are much reduced. The narrow and relatively long columns are packed with a noncompressible matrix of fine glass or plastic beads coated with a thin layer of the stationary phase. Alternatively, matrix may consist of silica whose available […]

HPLC Chromatographic Techniques Separate Amino Acids, Peptides, and Proteins

In high-performance liquid chromatography (HPLC), a liquid solvent containing a mixture of molecules to be identified is passed through a column densely packed with a small-diameter insoluble bead-like resin. In column chromatography, the smaller and more tightly packed the resin beads, the greater the resolution of the separation technique. In HPLC, the resin is so […]

The Human Genome Project

The Human Genome Project is a large international effort aimed at determining the sequence of the entire human genome of 3,200,000,000 base pair. But it is much more. Other aims include the creation of physical and genetic maps of the genome, sequencing the genomes of model organisms, developing technology for sequencing and informatics for understanding […]